Abstract | OBJECTIVE: METHODS: Ninety cases of postmenopausal osteoporosis were randomized into a warm acupuncture group, an electroacupuncture group and a medication group, 30 cases in each group. In the warm acupuncture group and the electroacupuncture group, Dazhu ( BL 11), Shenshu (BL 23) and Xuanzhong (GB 39) were selected bilaterally and stimulated with the warm acupuncture and electroacupuncture therapies respectively, once a day for 30 days totally. In the medication group, caltrate-D tablets were prescribed, 600 mg, once a day for 30 days totally. The changes in the bone density T value, visual analogue scale (VAS) score, serum insulin like growth factor 1 (IGF-1), interleukin 6 (IL-6) and tumor necrosis factor ( TNF-alpha) were observed before and after treatment in the three groups. RESULTS: (1) The bone density T value in the patients of postmenopausal osteoporosis did not change obviously after 30 days treatment with the three therapies; (2) VAS score was all reduced after treatment, in which, the result in the warm acupuncture group was the most obvious (6.73 +/- 0.24 before treatment vs 4.43 +/- 0.26 after treatment). The value after treatment in the warm acupuncture group was different significantly as compared with the electroacupuncture group (5.13 +/- 0.31) and the medication group (5.17 +/- 0.33, both P < 0.05). (3) The level of serum IGF-1 was improved after treatment in the warm acupuncture therapy [(119.5 +/- 20.1) ng/mL before treatment vs (156.5 +/- 23.9) ng/mL after treatment], which was more apparent as compared with the electroacupuncture group [(136.3 +/- 24.5) ng/mL] and the medication group [(127.7 +/- 22.1) ng/mL, all P < 0.05]. Concerning to reducing the levels of IL-6 and TNF-alpha in serum, the results in the warm acupuncture group were superior to the other two groups (all P < 0.05). CONCLUSION:
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Authors | Guo-Wei Cai, Jing Li, Xiao-Juan Xu, Yuan-Zhi Xue, Gang Li, Man Wu, Peng-Fei Li |
Journal | Zhongguo zhen jiu = Chinese acupuncture & moxibustion
(Zhongguo Zhen Jiu)
Vol. 34
Issue 1
Pg. 25-7
(Jan 2014)
ISSN: 0255-2930 [Print] China |
PMID | 24673048
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Interleukin-6
- Tumor Necrosis Factor-alpha
- Insulin-Like Growth Factor I
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Topics |
- Acupuncture Therapy
(methods)
- Bone Density
- Female
- Humans
- Insulin-Like Growth Factor I
(metabolism)
- Interleukin-6
(blood)
- Middle Aged
- Osteoporosis, Postmenopausal
(blood, physiopathology, therapy)
- Pain Management
- Tumor Necrosis Factor-alpha
(blood)
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