Tracheobronchial amyloidosis managed with multimodality therapies.

Abstract

Amyloidosis is a systemic disease involving abnormal extracellular deposition of amyloid and autologous fibrillar protein material in β-pleated sheets. Accumulation of this abnormal protein leads to organ dysfunction, although respiratory tract involvement is rare. We present two cases of tracheobronchial amyloidosis successfully treated with surgery and radiation.

• Authors: Philip Sommer, Gagan Kumar, Randolph J Lipchik, Jayshil J Patel
• Journal: Therapeutic advances in respiratory disease (Ther Adv Respir Dis) Vol. 8 Issue 2 Pg. 48-52 (Apr 2014) ISSN: 1753-4666 [Electronic] England
• PMID: 24594977 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Aged
• Amyloidosis (diagnosis, therapy)
• Bronchial Diseases (diagnosis, therapy)
• Bronchoscopy
• Combined Modality Therapy
• Debridement (instrumentation)
• Dose Fractionation, Radiation
• Female
• Humans
• Lasers, Solid-State (therapeutic use)
• Male
• Middle Aged
• Tomography, X-Ray Computed
• Tracheal Diseases (diagnosis, therapy)
• Treatment Outcome