Abstract | BACKGROUND: METHODS: Eight gastrointestinal fistula patients scheduled to undergo percutaneous abscess sump drainage were enrolled prospectively to measure albumin synthesis rates at different stages of the inflammatory response (immediately after diagnosis and 7 d following sump drainage when clinical signs of intra-abdominal sepsis had been eradicated). Eight age-, sex-, and body mass index-matched intestinal fistula patients were studied as control patients. Consecutive arterial blood samples were drawn during a primed-constant infusion (priming dose: 4 micromol·kg(-1), infusion rate: 6 micromol·kg(-1)·min(-1)) to determine the incorporation rate of L-[ring-(2)H5]- phenylalanine directly into plasma albumin using gas chromatography/mass spectrometry analysis. RESULTS: CONCLUSION:
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Authors | Bo Zhou, Jianan Ren, Gang Han, Yu Chen, Jiye A, Guosheng Gu, Jun Chen, Gefei Wang, Jieshou Li |
Journal | Surgical infections
(Surg Infect (Larchmt))
Vol. 15
Issue 2
Pg. 111-7
(Apr 2014)
ISSN: 1557-8674 [Electronic] United States |
PMID | 24460539
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Albumins
- Triiodothyronine
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Topics |
- Abdominal Abscess
(complications, metabolism, physiopathology)
- Adult
- Albumins
(analysis, metabolism)
- Case-Control Studies
- Digestive System Fistula
(complications, metabolism, physiopathology)
- Female
- Humans
- Hypoalbuminemia
(metabolism, physiopathology)
- Male
- Triiodothyronine
(blood)
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