Abstract | BACKGROUND: METHODS: RESULTS: CONCLUSIONS:
Tigecycline appears to be an effective therapy for severe infections due to CPKP in critically ill patients. Mortality is related to the severity of the underlying disease. We observed no benefit from a higher maintenance dose of tigecycline, although the number of patients included in the study was too small to draw any general conclusions in this regard.
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Authors | B Balandin Moreno, I Fernández Simón, V Pintado García, I Sánchez Romero, B Isidoro Fernández, M A Romera Ortega, S Alcántara Carmona, M Pérez Redondo, P Galdos Anuncibay |
Journal | Scandinavian journal of infectious diseases
(Scand J Infect Dis)
Vol. 46
Issue 3
Pg. 175-80
(Mar 2014)
ISSN: 1651-1980 [Electronic] England |
PMID | 24354959
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Bacterial Proteins
- Tigecycline
- beta-Lactamases
- carbapenemase
- Minocycline
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Topics |
- Adult
- Aged
- Anti-Bacterial Agents
(adverse effects, pharmacology, therapeutic use)
- Bacterial Proteins
(biosynthesis)
- Critical Illness
- Drug Resistance, Multiple, Bacterial
- Female
- Humans
- Klebsiella Infections
(drug therapy, microbiology)
- Klebsiella pneumoniae
(drug effects, enzymology, isolation & purification)
- Male
- Middle Aged
- Minocycline
(adverse effects, analogs & derivatives, pharmacology, therapeutic use)
- Retrospective Studies
- Tigecycline
- beta-Lactamases
(biosynthesis)
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