Functional pituitary tumors masquerading as primary glaucoma and effect of hypophysectomy on intraocular tension.

Abstract

We report 2 bilateral cases that presented as primary ocular hypertension and primary angle-closure glaucoma, respectively; however, they were subsequently discovered to be harboring secretory pituitary tumors. After transsphenoidal tumor resection, intraocular pressures (IOPs) in all 4 eyes returned to normal levels. Sudden rise in IOP then again served as a primary manifestation of relapse in the second patient with growth hormone secreting pituitary tumor. It was not found feasible for resurgery; thus, patient needed trabeculectomy in both eyes to achieve an optimum control of intraocular tension. We conclude that pituitary adenomas may mimic primary glaucoma without producing vertical hemianopia and cause a reversible rise in IOP. Furthermore, a careful ongoing expert ophthalmologic assessment may serve as a useful clinical marker for early relapse in these tumors.

• Authors: Shikha Gupta, Ramanjit Sihota, Viney Gupta, Tanuj Dada, Varun Gogia, Ajay Sharma
• Journal: Journal of glaucoma (J Glaucoma) Vol. 24 Issue 3 Pg. e7-13 (Mar 2015) ISSN: 1536-481X [Electronic] United States
• PMID: 23970340 (Publication Type: Case Reports, Journal Article)

Topics

• ACTH-Secreting Pituitary Adenoma (diagnosis, surgery)
• Adenoma (diagnosis, surgery)
• Adult
• Diagnosis, Differential
• Female
• Glaucoma, Angle-Closure (diagnosis, surgery)
• Humans
• Hypophysectomy
• Intraocular Pressure (physiology)
• Male
• Middle Aged
• Ocular Hypertension (diagnosis, surgery)
• Trabeculectomy
• Visual Acuity (physiology)
• Visual Fields (physiology)