[A case of Crohn's disease concomitant with IgA nephropathy].

Abstract

A 34-year-old woman with underlying IgA nephropathy was admitted to our hospital with chief complaints of abdominal pain and pyrexia. Computed tomography showed increased mural thickness of the ileum and increased mesenteric fat density. Colonoscopic findings revealed a longitudinal ulcer in the terminal ileum and irregularly shaped ulcers and a longitudinal ulcer scar in the descending colon. Histopathological analysis of biopsy specimens from the ileum and descending colon showed non-caseating epithelioid cell granuloma. On the basis of these findings, the condition of the patient was diagnosed as ileocolonic Crohn's disease, and the patient received parenteral nutrition, followed by elemental diet. The patient was responsive to nutrition therapy, and the amount of uric protein decreased as her Crohn's disease activity index decreased. In conclusion, we assume that the Crohn's disease activity correlated with that of IgA nephropathy.

• Authors: Osamu Arai, Norikuni Shibata, Makoto Kuboki, Hiroshi Ikeda, Kenji Omoto
• Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology (Nihon Shokakibyo Gakkai Zasshi) Vol. 110 Issue 7 Pg. 1265-71 (Jul 2013) ISSN: 0446-6586 [Print] Japan
• PMID: 23831657 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Adult
• Crohn Disease (complications)
• Female
• Glomerulonephritis, IGA (complications)
• Humans