Detection of varicella-zoster virus DNA in the iris of a zoster sine herpete patient.

Abstract

A 55-year-old man presented with unilateral iridocyclitis and elevated intraocular pressure (IOP) in his right eye. Varicella-zoster virus (VZV) DNA was detected by polymerase chain reaction (PCR) in the iris of a patient of Zoster Sine Herpete. No symptoms or signs of herpes zoster like neuralgia or cutaneous eruptions on forehead were noted. His iridocyclitis was treated and responded well with systemic and topical acyclovior as well as topical steroid. However, the marked elevated IOP could not be controlled by maximal dosage of anti-glaucomatous medicine. The patient underwent trabeculectomy to control his IOP. Samples of aqueous humor and iris tissue were obtained and VZV was checked by PCR. VZV virus DNA was detected from samples of the aqueous humor and iris tissue patient of Zoster Sine Herpete by PCR analysis.

• Authors: Mei-Ju Chen, Ko-Hua Chen, Yu-Mei Chung, An-Fei Li, Ching-Kuang Chou, Wen-Ming Hsu
• Journal: International journal of biomedical science : IJBS (Int J Biomed Sci) Vol. 2 Issue 3 Pg. 302-4 (Sep 2006) ISSN: 1550-9702 [Print] United States
• PMID: 23674996 (Publication Type: Case Reports)