[Heparins and skin reactions: from diagnostic to management].

Abstract

The use of heparins in the prophylaxis and treatment of thromboembolic diseases shows non-negligible risks of cutaneous lesions, which are very frequently underestimated by physicians. As this risk often originates from either delayed-type hypersensitivity reactions or life-threatening heparin-induced thrombocytopenia, a quick diagnosis and an adapted management are thus crucial. Furthermore, as most cases are emergencies, allergologic testing cannot be considered in the first place. In this context, an overview of the therapeutic as well as management recommendations is presented, taking into account the most recent treatments.

• Authors: Neda Barouti, Isabelle Masouyé, Wolf-Henning Boehncke, Christa Prins
• Journal: Revue medicale suisse (Rev Med Suisse) Vol. 9 Issue 380 Pg. 705-6, 708-11 (Apr 03 2013) ISSN: 1660-9379 [Print] Switzerland
• Vernacular Title: Héparines et réactions cutanées: du diagnostic a la prise en charge.
• PMID: 23621039 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anticoagulants
• Heparin

Topics

• Anticoagulants (adverse effects, therapeutic use)
• Drug Eruptions (diagnosis, etiology, pathology)
• Heparin (adverse effects, therapeutic use)
• Humans
• Hypersensitivity, Delayed (chemically induced)
• Thrombocytopenia (chemically induced)
• Thromboembolism (drug therapy)