Effectiveness of a calcium sodium phosphosilicate-containing prophylaxis paste in reducing dentine hypersensitivity immediately and 4 weeks after a single application: a double-blind randomized controlled trial.

Abstract

AIMS:

The aim of this single-site, randomized, controlled, double-blind, 3-arm parallel study was to determine the effectiveness of a prophylaxis paste containing 15% calcium sodium phosphosilicate (CSPS; NovaMin(®) ) with and without fluoride in reducing dentine hypersensitivity immediately after a single application and 28 days following dental scaling and root planing.

MATERIALS & METHODS:

Overall, 151 subjects were enrolled in this study. All subjects received a scaling and root planing procedure followed by a final prophylaxis step using one of three different prophylaxis pastes: Test-A (15% NovaMin(®) and NaF), Test-B (15% NovaMin(®) ) and a control. Dentine hypersensitivity was assessed by tactile stimulus (Yeaple Probe(®) ) and by air blast (Schiff scale) at baseline, immediately after and 28 days after a prophylaxis procedure. One hundred and forty-nine subjects completed the study.

RESULTS:

Subjects having received the test prophylaxis pastes showed statistically lower (anova, p < 0.05) dentine hypersensitivity compared with the control group immediately after the prophylaxis procedure (Yeaple Probe(®) : Test-A = 20.9 ± 12.6, Test-B = 22.7 ± 12.9, Control=11.2 ± 3.1; Schiff score: Test-A = 1.1 ± 0.6, Test-B = 1.1 ± 0.6, Control = 2.0 ± 0.7) and after 28 days (Yeaple probe: Test-A = 21.5 ± 11.9, Test-B = 20.6 ± 11.3, Control = 11.8 ± 6.0; Schiff score: Test-A = 1.0 ± 0.6, Test-B = 1.0 ± 0.6, Control = 2.0 ± 0.7).

CONCLUSIONS:

In conclusion, the single application of both fluoridated and non-fluoridated prophylaxis pastes containing 15% CSPS (NovaMin(®) ) provided a significant reduction of dentine hypersensitivity up to at least 28 days.

• Authors: Klaus W Neuhaus, Jeffery L Milleman, Kimberly R Milleman, Kimberly A Mongiello, Thomas C Simonton, Courtney E Clark, Howard M Proskin, Rainer Seemann
• Journal: Journal of clinical periodontology (J Clin Periodontol) Vol. 40 Issue 4 Pg. 349-57 (Apr 2013) ISSN: 1600-051X [Electronic] United States
• PMID: 23414245 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: © 2013 John Wiley & Sons A/S.

Chemical References

• Dentin Desensitizing Agents
• NovaMin
• Toothpastes
• Sodium Fluoride

Topics

• Adolescent
• Adult
• Aged
• Analysis of Variance
• Dental Prophylaxis (methods)
• Dental Scaling (adverse effects, methods)
• Dentin Desensitizing Agents (chemistry, therapeutic use)
• Dentin Sensitivity (etiology, prevention & control)
• Double-Blind Method
• Female
• Glass (chemistry)
• Humans
• Male
• Middle Aged
• Sodium Fluoride (therapeutic use)
• Surveys and Questionnaires
• Time Factors
• Toothpastes (chemistry, therapeutic use)
• Young Adult