[Treatment strategy for stage I testicular germ cell tumor].

Abstract

Most stage I testicular germ cell tumors are curable by orchiectomy alone. However, some tumors recur and require subsequent treatment. The point for the management of stage I testicular germ cell tumors is how to reduce the recurrence rate by appropriate adjuvant treatment with less adverse events. The strategy for stage I seminoma and stage I nonseminoma is different. The adjuvant treatment options include radiotherapy and 1-2 courses of carboplatin for seminoma and retroperitoneal lymph node dissection (RPLND) and 1-2 courses of bleomycin, etoposide and cisplatin chemotherapy for nonseminoma. This review discusses recent literature on adjuvant treatment and updates the consensus for the management of stage I testicular germ cell tumor.

• Authors: Yasutomo Nakai, Akira Nagahara, Motohide Uemura, Hitoshi Takayama, Norio Nonomura
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 58 Issue 12 Pg. 715-20 (Dec 2012) ISSN: 0018-1994 [Print] Japan
• PMID: 23328172 (Publication Type: English Abstract, Journal Article)

Topics

• Chemotherapy, Adjuvant
• Humans
• Male
• Neoplasm Staging
• Neoplasms, Germ Cell and Embryonal (therapy)
• Testicular Neoplasms (therapy)