Pregnancy outcome among women universally screened for gestational diabetes mellitus with a lime-flavoured drink.

Abstract

We performed a prospective study involving 400 consecutive pregnant patients to determine whether the administration of a lime-flavoured glucose drink followed by a blood test 1 h later was a better method of screening for gestational diabetes (GDM) than the use of selective screening based on risk factors (maternal age over 30 years, East Indian ancestry and obesity). Complete data were available for 388 women, 76 were screen positive (1 h blood glucose ≥ 140 mg/dl) and GDM was diagnosed in 42 (using a 75 g oral glucose tolerance test) giving a positive predictive value of 55%. Selective screening applied to the same population would have identified only 34 cases, eight fewer with GDM. In this population, the use of the lime-flavoured glucose drink detected approximately 25% more cases of GDM than selective screening based on risk factors. Caesarean sections were performed in 18 (42.8%) of women with gestational diabetes. None of the four perinatal deaths was observed among the women with gestational diabetes.

• Authors: B Bassaw, N Mohammed, S Ramsewak, L Bassawh, A Khan, M Bhola, A Chekuri
• Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (J Obstet Gynaecol) Vol. 32 Issue 5 Pg. 422-5 (Jul 2012) ISSN: 1364-6893 [Electronic] England
• PMID: 22663310 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Blood Glucose
• Glucose

Topics

• Adolescent
• Adult
• Beverages
• Blood Glucose (analysis)
• Cesarean Section (statistics & numerical data)
• Diabetes, Gestational (diagnosis, epidemiology)
• Female
• Glucose (administration & dosage)
• Glucose Tolerance Test (methods)
• Humans
• Mass Screening
• Maternal Age
• Obesity (complications)
• Pregnancy
• Pregnancy Outcome
• Prospective Studies