Abstract |
The purpose of this study was to examine the lipoprotein (a) [Lp(a)] levels in children with migraine to see a possible relationship between migraine and stroke via high Lp(a) levels. Plasma levels of Lp(a) were determined in 63 patients and age-matched control subjects. The mean age in the control group was 10.57 ± 3.63 years and 11.51 ± 3.19 years in the migraine patient group. The mean Lp(a) levels in control group were 10.36 ± 10.41 ng/mL and 17.09 ± 12.12 ng/mL in migraine group (P < 0.05). The median Lp(a) level in the control group was 49.38 ng/mL and was 77.62 ng/mL in the migraine group (P < 0.05). Twelve patients (19%) had Lp(a) levels of >30 ng/mL in the migraine group and 4 (6.3%) in the control group (P < 0.05). Several prothrombotic factors related to an increased risk of stroke have been studied in migraine patients. It has recently been reported that high Lp(a) concentrations represent a risk factor for migraine, thus establishing a novel plausible link between migraine and stroke. The current study suggests evidence of high Lp(a) concentrations in childhood migraine; perhaps a novel link exists between migraine and stroke.
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Authors | Serap Teber, Ömer Bektas, Arzu Yılmaz, Erhan Aksoy, Nejat Akar, Gülhis Deda |
Journal | Pediatric neurology
(Pediatr Neurol)
Vol. 45
Issue 4
Pg. 225-8
(Oct 2011)
ISSN: 1873-5150 [Electronic] United States |
PMID | 21907882
(Publication Type: Journal Article)
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Copyright | Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Adolescent
- Brain Ischemia
(blood, etiology)
- Child
- Child, Preschool
- Female
- Humans
- Lipoprotein(a)
(blood)
- Male
- Migraine Disorders
(blood, complications)
- Risk Factors
- Stroke
(blood, etiology)
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