Abstract | PURPOSE: METHODS: A retrospective review of 30 LABC patients who underwent SSM and IABR between 1997 to 2007 was performed. Data were drawn from patient records and the University of British Columbia (UBC) Breast Reconstruction and British Columbia Cancer Agency databases. RESULTS: All 30 patients received neoadjuvant chemotherapy, preoperative radiotherapy, SSM, and IABR. Fifteen patients (50%) had stage IIIA disease, 13 (43%) stage IIIB, and 2 (6.7%) stage IIIC. Reconstruction types included the pedicled transverse rectus myocutaneous flap (n = 24), the latissimus dorsi flap (n = 5), and a combination of transverse rectus myocutaneous and latissimus dorsi flap (n = 1). The median follow-up was 3.51 years (range 1-9.4 years). Local complications included mastectomy flap necrosis (n = 3), partial flap necrosis (n = 1), fat necrosis (n = 1), seroma (n = 3), infection (n = 2), and flap fibrosis (n = 1). The incidence of donor site complications was 20%. Overall 5-year actuarial locoregional relapse-free, distant relapse-free, and disease-specific survival rates were 80, 65, and 68%, respectively. Excellent or good physician-rated aesthetic results were achieved in 66% of patients. CONCLUSIONS:
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Authors | Adelyn L Ho, Scott Tyldesley, Sheina A Macadam, Peter A Lennox |
Journal | Annals of surgical oncology
(Ann Surg Oncol)
Vol. 19
Issue 3
Pg. 892-900
(Mar 2012)
ISSN: 1534-4681 [Electronic] United States |
PMID | 21845498
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Breast
(radiation effects)
- Breast Neoplasms
(pathology, radiotherapy, surgery)
- Esthetics
- Female
- Humans
- Mammaplasty
(methods)
- Mastectomy
(methods)
- Middle Aged
- Neoadjuvant Therapy
- Neoplasm Recurrence, Local
- Surgical Flaps
(adverse effects)
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