Abstract | BACKGROUND: PATIENTS AND METHODS: JT-95 staining was performed in 9 PTC and 20 follicular type tumors to investigate the relationship between the expression of sFN and the frequency of LNM. RESULTS: There were 11 cases with LNM from 23 malignant tumors, and no cases of LNM from 6 benign follicular type tumors. The staining scores by JT-95 of the 11 tumors with LNM were 5+ in 4 cases, and 6+ in 7 cases. On the other hand, the scores of 12 malignant tumors without LNM were <4+ in all cases. CONCLUSION: An increase of sFN expression in thyroid malignancies is correlated with LNM.
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Authors | Hiroshi Takeyama, Shigeya Kyoda, Tomoyoshi Okamoto, Yoshinobu Manome, Michiko Watanabe, Satoki Kinoshita, Ken Uchida, Atsuhiko Sakamoto, Toshiaki Morikawa |
Journal | Anticancer research
(Anticancer Res)
Vol. 31
Issue 4
Pg. 1395-8
(Apr 2011)
ISSN: 1791-7530 [Electronic] Greece |
PMID | 21508391
(Publication Type: Journal Article)
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Chemical References |
- Antibodies, Monoclonal
- Fibronectins
- N-Acetylneuraminic Acid
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Topics |
- Adenocarcinoma, Follicular
(immunology, metabolism, secondary)
- Adult
- Antibodies, Monoclonal
(immunology, metabolism)
- Carcinoma, Papillary
(immunology, metabolism, secondary)
- Female
- Fibronectins
(immunology, metabolism)
- Follow-Up Studies
- Humans
- Immunoenzyme Techniques
- Lymphatic Metastasis
- Male
- Middle Aged
- N-Acetylneuraminic Acid
(immunology, metabolism)
- Prognosis
- Thyroid Neoplasms
(immunology, metabolism, pathology)
- Young Adult
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