Abstract | BACKGROUND: METHOD: A comprehensive literature search was conducted from the websites of Pubmed Central, the US National Library of Medicine's digital archive of life sciences literature (http://www.pubmedcentral.nih.gov/) and the National Library of Medicine (http://www.ncbl.nlm.nih.gov). The data was also assessed from journals and books that published relevant articles in this field. RESULT:
Hepcidin regulates iron uptake constantly on a daily basis, to maintain sufficient iron stores for erythropoiesis. Hepcidin, by its iron regulatory action on iron metabolism may be expected to have an important role in immune regulation, inflammatory diseases and malignancies. Hepcidin is the underlying cause of anemia in these clinical settings. CONCLUSION:
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Authors | Bhawna Singh, Sarika Arora, Poonam Agrawal, S K Gupta |
Journal | Clinica chimica acta; international journal of clinical chemistry
(Clin Chim Acta)
Vol. 412
Issue 11-12
Pg. 823-30
(May 12 2011)
ISSN: 1873-3492 [Electronic] Netherlands |
PMID | 21333642
(Publication Type: Journal Article, Review)
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Copyright | Copyright © 2011 Elsevier B.V. All rights reserved. |
Chemical References |
- Antimicrobial Cationic Peptides
- HAMP protein, human
- Hepcidins
- Hormones
- Iron
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Topics |
- Animals
- Antimicrobial Cationic Peptides
(analysis, chemistry, genetics, metabolism)
- Clinical Chemistry Tests
- Hepcidins
- Homeostasis
- Hormones
(chemistry, genetics, metabolism)
- Humans
- Immunity, Innate
- Iron
(metabolism)
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