Abstract | BACKGROUND/AIMS: The eye may be infected from external sources or through intra-ocular invasion of micro-organisms carried by the blood stream. This study was undertaken to isolate and identify the specific bacterial pathogens causing ocular infections and to determine their in-vitro antibacterial susceptibilities to commonly used antibacterial agents. MATERIALS AND METHODS: RESULTS: A total of 756 patients with bacterial ocular infections were analyzed, of which 462(61%) eyes had adnexal bacterial infection, 217(28.7%) had corneal infection, 6 (0.8%) had scleral involvement and the remaining 71(9.39%) eyes had infection of the intra-ocular tissues. The predominant bacterial species isolated was S. aureus (195 of 776; 25%) followed by S. pneumoniae (169 of 776; 21.78%) and coagulase negative staphylococci (142 of 776; 18.3%). The largest number of gram-positive isolates were susceptible to cefazolin (545 of 624; 87.34%), chloramphenicol (522 of 624; 83.65%) and gatifloxacin (511 of 624; 81.89%) and gram-negative isolates were to amikacin (127 of 136; 93.38%), gatifloxacin (125 of 136; 91.91%) and ofloxacin (119 of 136; 87.5%), while aerobic actinomycetes were to amikacin (100%), gatifloxacin (14 of 16; 87.5%), chloramphenicol (14 of 16; 87.5%) and ofloxacin (13 of 16; 81.25%). CONCLUSIONS:
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Authors | S Ramesh, R Ramakrishnan, M Jayahar Bharathi, M Amuthan, S Viswanathan |
Journal | Indian journal of pathology & microbiology
(Indian J Pathol Microbiol)
2010 Apr-Jun
Vol. 53
Issue 2
Pg. 281-6
ISSN: 0974-5130 [Electronic] India |
PMID | 20551533
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Anti-Bacterial Agents
(pharmacology)
- Bacteria
(classification, growth & development, isolation & purification)
- Eye Infections, Bacterial
(epidemiology, microbiology)
- Humans
- India
(epidemiology)
- Microbial Sensitivity Tests
- Microscopy
- Prevalence
- Retrospective Studies
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