Ketogenic diet for treatment of epilepsy.

Abstract

QUESTION:

Families of children with epilepsy now ask about the ketogenic diet at clinic visits. Is it effective and safe to use for treatment of epilepsy?

ANSWER:

The ketogenic diet can be considered an option for children with intractable epilepsy who use multiple antiepileptic drugs. It is a treatment of choice for seizures associated with glucose transporter protein deficiency syndrome (ie, De Vivo disease) and pyruvate dehydrogenase complex deficiency. The diet's strictness, unpalatability, and side effects limit its use, adversely affecting patients' compliance and clinical efficacy.

• Authors: Alexander L Rogovik, Ran D Goldman
• Journal: Canadian family physician Medecin de famille canadien (Can Fam Physician) Vol. 56 Issue 6 Pg. 540-2 (Jun 2010) ISSN: 1715-5258 [Electronic] Canada
• PMID: 20547519 (Publication Type: Journal Article)

Topics

• Adult
• Child
• Child, Preschool
• Clinical Trials as Topic
• Diet, Ketogenic (adverse effects, methods)
• Epilepsy (diet therapy)
• Evidence-Based Medicine
• Humans
• Seizures (prevention & control)