Patients with impaired hepatic functional reserve when submitted to surgeries may have high rates of morbidity and mortality. Pre-existing
liver disease should be detected without need for invasive methods. Clinical history and physical examination provide important clues. Laboratory liver function is not necessary unless there are changes in history or physical examination.
Liver disease has many effects on surgery and
anesthesia. A decrease in oxygenation and increased risk of
liver dysfunction can be caused by
anesthesia,
hemorrhage,
hypoxemia,
hypotension, vasoactive drugs or the patient's position on the
operating table during and after surgery. Emergency surgery is a major predictor of poor prognosis as well as
sepsis and reoperations. The nature of
liver disease, severity and type of surgery to be performed should take into account for a correct preoperative preparation. Some actions must be taken at preoperative to decrease chances of complications in patients with
liver disease undergoing
surgical procedures. Very close attention should be given to coagulopathy,
encephalopathy,
ascites, renal and pulmonary dysfunction, spontaneous bacterial
peritonitis and
esophageal varices. Patients with Child-Pugh score C and MELD>15 should not undergo elective surgery. Patients with Child-Pugh score B and MELD 10 to 15 may undergo
minor surgical procedures with care in cases of extreme necessity. Patients with Child-Pugh score A and MELD<10 may be submitted to elective surgery.