[A case report of alverine-citrate-induced acute hepatitis].

Abstract

Alverine citrate is one of the most commonly used antispasmodic drugs for patients with irritable bowel syndrome. Alverine-citrate-induced hepatotoxicity is extremely rare, with only a few cases having been reported worldwide. We present a case of a 75-year-old female patient who experienced complicated jaundice and abdominal discomfort after taking alverine citrate. Other causes of hepatitis were ruled out and the results of the liver function test returned to normal after ceasing the drug. This is the first case report in Korea of alverine-citrate-induced hepatotoxicity.

• Authors: Jee Young Han, Jin Woo Lee, Joon Mee Kim, Kowoon Joo, Ung Chon, Jung Il Lee, Seok Jeong, Don Haeng Lee, Young Soo Kim, Kyung Sun Min
• Journal: The Korean journal of hepatology (Korean J Hepatol) Vol. 16 Issue 1 Pg. 75-8 (Mar 2010) ISSN: 1738-222X [Print] Korea (South)
• PMID: 20375645 (Publication Type: Case Reports, Journal Article)

Chemical References

• Citrates
• Parasympatholytics
• Propylamines
• alverine

Topics

• Acute Disease
• Aged
• Chemical and Drug Induced Liver Injury (diagnosis, etiology, pathology)
• Citrates (adverse effects, therapeutic use)
• Female
• Humans
• Irritable Bowel Syndrome (drug therapy)
• Liver Function Tests
• Parasympatholytics (adverse effects, therapeutic use)
• Propylamines (adverse effects, therapeutic use)
• Tomography, X-Ray Computed