Abstract | BACKGROUND: AIM: To review the literature on the effect of various weight reducing modalities on manifestations of GERD in obese patients. METHODS: RESULTS: With regard to diet/lifestyle intervention (conservative), four of seven studies reported an improvement of GERD. For Roux-en-Y gastric bypass, a positive effect on GERD was found in all studies, although this was mainly evaluated by questionnaires. In contrast, for vertical banded gastroplasty, no change or even an increase of GERD was noted, whereas the results for laparoscopic adjustable gastric banding were conflicting. CONCLUSIONS: Dietary and lifestyle intervention may improve GERD in obese patients; however, the most favourable effect is likely to be found after bariatric surgery, especially after Roux-en-Y gastric bypass. Future studies need to elucidate for which GERD patients laparoscopic adjustable gastric banding might have a beneficial effect and how they can be identified preoperatively.
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Authors | N L De Groot, J S Burgerhart, P C Van De Meeberg, D R de Vries, A J P M Smout, P D Siersema |
Journal | Alimentary pharmacology & therapeutics
(Aliment Pharmacol Ther)
Vol. 30
Issue 11-12
Pg. 1091-102
(Dec 01 2009)
ISSN: 1365-2036 [Electronic] England |
PMID | 19758397
(Publication Type: Comparative Study, Journal Article, Review, Systematic Review)
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Topics |
- Bariatric Surgery
(adverse effects)
- Body Mass Index
- Diet, Reducing
(adverse effects)
- Gastroesophageal Reflux
(diet therapy, surgery)
- Humans
- Obesity, Morbid
(complications, diet therapy, surgery)
- Risk Factors
- Treatment Outcome
- Weight Loss
(physiology)
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