Abstract | BACKGROUND: MATERIALS AND METHODS: The study included 619 women classified according to their blood pressure values. IgG anti- oxidized LDL antibodies were measured by enzyme-linked immunosorbent assay and the women were classified as being above or below the 50th percentile. RESULTS:
Hypertension was present in 54.3% of the women. These women had significantly lower levels of IgG anti- oxidized LDL antibodies than the normotensive women (0.280 +/- 0.117 vs. 0.336 +/- 0.125, P < 0.001). Both systolic and the diastolic blood pressures showed a significant negative correlation with the levels of IgG anti- oxidized LDL antibodies (r = -0.204, P < 0.001; r = -0.225, P < 0.001, respectively). Women with IgG anti- oxidized LDL antibody levels above the 50th percentile had a lower prevalence of hypertension than those with IgG anti- oxidized LDL antibody levels below the 50th percentile (40.2% vs. 59.8%) (P < 0.001). CONCLUSIONS:
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Authors | L Garrido-Sánchez, E García-Fuentes, F Cardona, G Rojo-Martínez, F Soriguer, F J Tinahones |
Journal | European journal of clinical investigation
(Eur J Clin Invest)
Vol. 39
Issue 9
Pg. 800-6
(Sep 2009)
ISSN: 1365-2362 [Electronic] England |
PMID | 19674079
(Publication Type: Journal Article)
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Chemical References |
- Antibodies, Anti-Idiotypic
- Autoantibodies
- Lipoproteins, LDL
- anti-IgG
- oxidized low density lipoprotein
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Topics |
- Adolescent
- Adult
- Aged
- Antibodies, Anti-Idiotypic
(blood)
- Atherosclerosis
(immunology)
- Autoantibodies
(blood)
- Female
- Humans
- Hypertension
(blood, immunology)
- Lipoproteins, LDL
(blood, immunology)
- Middle Aged
- Reference Values
- Risk Factors
- Young Adult
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