Celiac disease-related antibodies in Italian children with epilepsy.

Abstract

Reports differ on the association between epilepsy and celiac disease, an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. In this study, 272 Italian children with epilepsy and 300 healthy children were screened for anti-gliadin and anti-transglutaminase immunoglobulin A and G; positive and borderline samples were tested for the presence of anti-endomysium antibodies. The prevalence of antibodies related to celiac disease was comparable to that of healthy controls. In keeping with this observation, Italian epileptic children should not be considered a group at risk for celiac disease.

• Authors: Lucio Giordano, Monica Valotti, Adonella Bosetti, Patrizia Accorsi, Luigi Caimi, Luisa Imberti
• Journal: Pediatric neurology (Pediatr Neurol) Vol. 41 Issue 1 Pg. 34-6 (Jul 2009) ISSN: 1873-5150 [Electronic] United States
• PMID: 19520271 (Publication Type: Journal Article)

Chemical References

• Autoantibodies
• Immunoglobulin A
• Immunoglobulin G
• Gliadin
• Transglutaminases

Topics

• Adolescent
• Autoantibodies (blood)
• Celiac Disease (blood, complications, immunology)
• Child
• Child, Preschool
• Enzyme-Linked Immunosorbent Assay
• Epilepsy (blood, complications, immunology)
• Female
• Gliadin (blood, immunology)
• Humans
• Immunoglobulin A (blood, immunology)
• Immunoglobulin G (blood, immunology)
• Infant
• Italy
• Male
• Risk Factors
• Transglutaminases (blood, immunology)