Abstract | BACKGROUND AND OBJECTIVE: PATIENTS AND METHODS: Thirty-nine patients were divided into three groups: G1, where the irradiations were done three times a week using low power laser; G2, where combined high and low power lasers were used three time a week; and G3, where patients received low power laser irradiation once a week. The low power LPT was done using an InGaAlP laser (660 nm/40 mW/6 J cm(-2)/0.24 J per point). In the combined protocol, the high power LPT was done using a GaAlAs laser (808 nm, 1 W/cm(2)). Oral mucositis was assessed at each LPT session in accordance to the oral-mucositis scale of the National Institute of the Cancer-Common Toxicity criteria (NIC-CTC). The patient self-assessed pain was measured by means of the visual analogue scale. RESULTS: All protocols of LPT led to the maintenance of oral mucositis scores in the same levels until the last RT session. Moreover, LPT three times a week also maintained the pain levels. However, the patients submitted to the once a week LPT had significant pain increase; and the association of low/high LPT led to increased healing time. CONCLUSIONS: These findings are desired when dealing with oncologic patients under RT avoiding unplanned radiation treatment breaks and additional hospital costs.
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Authors | Alyne Simões, Fernanda P Eduardo, Ana Claudia Luiz, Luana Campos, Pedro Henrique R N Sá, Márcio Cristófaro, Márcia M Marques, Carlos P Eduardo |
Journal | Lasers in surgery and medicine
(Lasers Surg Med)
Vol. 41
Issue 4
Pg. 264-70
(Apr 2009)
ISSN: 1096-9101 [Electronic] United States |
PMID | 19347940
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Topics |
- Administration, Topical
- Adolescent
- Adult
- Aged
- Female
- Head and Neck Neoplasms
(radiotherapy)
- Humans
- Low-Level Light Therapy
- Male
- Middle Aged
- Pain
(etiology, prevention & control)
- Pain Measurement
- Phototherapy
- Prospective Studies
- Radiation Injuries
(etiology, prevention & control)
- Radiotherapy
(adverse effects)
- Stomatitis
(classification, etiology, prevention & control)
- Young Adult
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