Abstract | BACKGROUND: METHODS: Since 2004, the Mayo Clinic (Rochester, MN) has had a standard reperfusion protocol for the treatment of patients with STEMI. During the study period, 767 patients presented with new or presumed new ST elevation or left bundle block. RESULTS: The diagnosis of STEMI was confirmed in 765 (99.7%) patients. Using the 99th percentile cutoff value, troponin T elevations occurred in 765 (100%) of 765 patients when serial samples were available. Creatine kinase-MB levels of twice or more the upper limit of normal occurred in 681 (90.1%) of 749 patients with serial samples for CK-MB, and CK equal or greater than twice the gender-specific upper limits of normal occurred in 521 (78.8%) of 661 patients with serial samples for CK available. CONCLUSION: The frequency of aborted myocardial infarction is 0% when using troponin at the 99th percentile cutoff as recommended by contemporary guidelines from the European Society of Cardiology (Nice, France) and American College of Cardiology (Washington, DC).
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Authors | Vlad C Vasile, Luciano Babuin, Henry H Ting, Malcolm R Bell, Nicholas M Orme, Brandon Y Yuan, Jose A Rio Perez, Jorge R Alegria, Fernanda Bellolio, Luis H Haro, Allan S Jaffe |
Journal | American heart journal
(Am Heart J)
Vol. 157
Issue 4
Pg. 636-41
(Apr 2009)
ISSN: 1097-6744 [Electronic] United States |
PMID | 19332189
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
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Topics |
- Biomarkers
(blood)
- Diagnosis, Differential
- Diagnostic Errors
- Humans
- Myocardial Infarction
(blood, diagnosis)
- Troponin
(blood)
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