Deep lamellar endothelial keratoplasty for iridocorneal endothelial syndrome in phakic eyes.

Abstract

OBJECTIVE:

To evaluate the efficacy and postoperative complications of deep lamellar endothelial keratoplasty (DLEK) for treating iridocorneal endothelial (ICE) syndrome in phakic eyes.

METHODS:

Retrospective noncomparative interventional case series. Seven consecutive patients (7 eyes) having ICE syndrome with clear or mildly opaque lens were treated using DLEK and were followed up for 9 to 20 months. Data collected included best spectacle-corrected visual acuity, intraocular pressure, corneal astigmatism, endothelial cell density, and peripheral iris and anterior chamber angles using ultrasonographic biomicroscopy.

RESULTS:

Corneas were clear in all eyes. No graft dislocation or lens injury occurred. During the follow-up period, 2 eyes developed cataract, 1 of which underwent phacoemulsification and intraocular lens implantation; 2 eyes had elevated intraocular pressure, 1 of which underwent filtering valve implant surgery; and 3 eyes showed progressive peripheral anterior synechiae. At the last follow-up, best spectacle-corrected visual acuity ranged from 20/67 to 20/30; the mean (SD) corneal astigmatism was 2.0 (0.7) diopters (D); and the mean (SD) corneal curvature was 44.6 (1.5) D. The mean (SD) endothelial cell density was 1917 (156) cells/mm(2) 9 months after surgery.

CONCLUSIONS:

DLEK is efficacious in the treatment of ICE syndrome in phakic eyes, with rapid visual rehabilitation and low incidence of postoperative complications. DLEK may be a good option for ICE syndrome in phakic eyes.

• Authors: Ting Huang, Yujuan Wang, Jianping Ji, Na Gao, Jiaqi Chen
• Journal: Archives of ophthalmology (Chicago, Ill. : 1960) (Arch Ophthalmol) Vol. 127 Issue 1 Pg. 33-6 (Jan 2009) ISSN: 1538-3601 [Electronic] United States
• PMID: 19139335 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adult
• Anterior Chamber (diagnostic imaging)
• Cell Count
• Corneal Diseases (physiopathology, surgery)
• Corneal Transplantation
• Endothelium, Corneal (pathology, transplantation)
• Female
• Follow-Up Studies
• Humans
• Intraocular Pressure (physiology)
• Iris Diseases (physiopathology, surgery)
• Lens, Crystalline (physiology)
• Male
• Microscopy, Acoustic
• Middle Aged
• Postoperative Complications
• Retrospective Studies
• Syndrome
• Tissue Donors
• Treatment Outcome
• Visual Acuity (physiology)