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Corneal Transplantation (Keratoplasty)

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Partial or total replacement of the CORNEA from one human or animal to another.

Also Known As:

Keratoplasty; Cornea Transplantation; Transplantation, Cornea; Cornea Transplantations; Corneal Grafting; Corneal Graftings; Corneal Transplantations; Graftings, Corneal; Keratoplasties; Keratoplasties, Lamellar; Lamellar Keratoplasties; Lamellar Keratoplasty; Transplantations, Cornea; Transplantations, Corneal; Grafting, Corneal; Keratoplasty, Lamellar; Transplantation, Corneal

Networked: 2560 relevant articles (137 outcomes, 151 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 8
- Transplantation: 55694
  - Tissue Transplantation: 290
    - Corneal Transplantation: 2560
      - Penetrating Keratoplasty: 2046
      - Epikeratophakia: 215
- Ophthalmologic Surgical Procedures: 6
  - Refractive Surgical Procedures: 994
    - Corneal Transplantation: 2560

Experts

1.	Sharma, Namrata: 32 articles (06/2015 - 07/2002)
2.	Vajpayee, Rasik B: 31 articles (11/2014 - 07/2002)
3.	Mehta, Jodhbir S: 25 articles (10/2015 - 09/2007)
4.	Feizi, Sepehr: 23 articles (10/2015 - 01/2009)
5.	Jhanji, Vishal: 23 articles (11/2014 - 06/2007)
6.	Seitz, B: 22 articles (06/2015 - 08/2000)
7.	Cursiefen, Claus: 22 articles (04/2015 - 10/2002)
8.	Shi, Weiyun: 21 articles (06/2015 - 01/2002)
9.	Price, Francis W: 20 articles (09/2015 - 06/2004)
10.	Wagoner, Michael D: 18 articles (11/2015 - 08/2004)

Related Diseases

1.	Astigmatism 01/01/2008 - "Arcuate incisions with the femtosecond laser on patients with high astigmatism subsequent to corneal transplantation are an effective and safe treatment." 01/01/1996 - "Following adjustment there was a significant reduction in median post-keratoplasty astigmatism from 6.00 DC to 2.50 DC (p < 0.001). " 11/01/1995 - "Combined corneal wedge resection and relaxing incisions appears to be effective in reducing high refractive astigmatism following corneal transplantation." 09/01/1996 - "Hot needle sectoral thermal keratoplasty appears to be safe and partially effective in reducing hyperopic astigmatism, but considerable postoperative regression may occur." 06/01/2009 - "Arcuate keratotomies performed with the femtosecond laser were effective in reducing post-keratoplasty astigmatism. "
2.	Keratoconus 08/01/1977 - "The best results were achieved with keratoplasties in corneal dystrophies (keratoconus included). " 09/01/2015 - "Traditionally, the mainstay of treatment for advanced keratoconus (KC) has been either penetrating or deep anterior lamellar keratoplasty (PK or DALK, respectively). " 05/01/2011 - "Deep anterior lamellar keratoplasty that uses the big-bubble technique is effective in patients with keratoconus. " 10/01/2010 - "Topography-guided conductive keratoplasty may be effective in reshaping corneal configuration in eyes with keratoconus, without serious complications, and possibly contributed to avoiding or delaying corneal transplantation." 04/01/2014 - "Our early results indicate that femtosecond laser-assisted deep anterior lamellar keratoplasty shows promise as a safe and effective surgical choice in the treatment of keratoconus."
3.	Infection 11/01/2013 - "Overall, 8.3% needed corneal grafting, which survived in 83.3% and eradicated infection in 100%. " 04/01/2015 - "Subsequently, we demonstrated the safety and efficacy of APCSs in human keratoplasty for a minimum follow-up period of 6 months, during which time no recurrence of infection was observed. " 02/01/1999 - "Infections were considered cured if there was no evidence of corneal infiltration for 1 month following keratoplasty. " 05/01/1976 - "Finally, the corneal infection was cured by an urgent perforating keratoplasty." 09/01/2014 - "The aim of this study was to evaluate the visual outcomes and graft survival rate after therapeutic keratoplasty performed for interface infection after Descemet stripping automated endothelial keratoplasty (DSAEK). "
4.	Cataract (Cataracts) 01/01/2013 - "To report a case of corneal graft failure due to epithelial ingrowth after an uneventful combined Descemet stripping automated endothelial keratoplasty (DSAEK) and phacoemulsification cataract surgery with intraocular lens implant treated successfully with a repeat DSAEK. " 03/01/2005 - "Frequency of cataract surgery after therapeutic keratoplasty was significantly greater than that following optical keratoplasty [68 (52%) versus 47 (21%); P<0.001]. " 04/01/2003 - "To determine the efficacy of planned secondary cataract surgery after keratoplasty. " 01/01/1982 - "Therefore, when the retina is intact, an improvement in visual acuity can be expected in only 52% of patients after perforating keratoplasty, visual iridectomy or cataract operation. " 12/01/2014 - "The study analyzed post-keratoplasty eyes after cataract surgery and toric IOL (Acrysof SN60AT or T-flex 623T/573T) implantation. "
5.	Cicatrix (Scar) 06/21/2009 - "microkeratome-assisted anterior lamellar keratoplasty seems to be safe and effective to remove corneal scars and reduce high degree irregular astigmia, moreover, to improve visual acuity." 11/01/2011 - "Hemi-automated lamellar keratoplasty is an effective and safe surgical procedure in the treatment of corneas with irregular topographic profiles with varying depths of anterior stromal scarring. " 05/01/1996 - "PTK is a relatively safe and effective means of treating corneal scars and thereby may offer an alternative to corneal transplantation." 12/01/2011 - "To demonstrate the efficacy of a planned near-Descemet dissection deep anterior lamellar keratoplasty (nddDALK) in posthydrops corneal scarring. " 09/01/2009 - "The purpose of this study was to evaluate outcomes of Descemet's stripping automated endothelial keratoplasty (DSAEK) using anterior stromal flawed (ASF) donor corneas that were unsuitable for use in full-thickness penetrating keratoplasty as a result of stromal scars, pterygia, or previous corneal refractive surgery and to compare results with DSAEK using standard tissue. "

Related Drugs and Biologics

1.	Mitomycin (Mitomycin-C)
2.	Cyclosporine (Ciclosporin)
3.	Anti-Bacterial Agents (Antibiotics)
4.	Alkalies
5.	Amphotericin B (Amphotericin)
6.	voriconazole (Vfend)
7.	Itraconazole (Sporanox)
8.	Tacrolimus (Prograf)
9.	propamidine isethionate
10.	Holmium

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Corneal Transplantation (Keratoplasty)
3.	Lasers (Laser)
4.	Laser In Situ Keratomileusis (LASIK)
5.	Photorefractive Keratectomy