Phacoemulsification

A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. The small incision allows the surgeon to use very few or even no stitches to close the tiny wound. There is usually no need for hospitalization and patients may resume most activities within days. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)

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Networked: 3376 relevant articles (255 outcomes, 423 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Lam, Dennis S C: 25 articles (01/2015 - 06/2002)
2.	Yao, Ke: 21 articles (04/2015 - 12/2003)
3.	Dick, H Burkhard: 19 articles (09/2015 - 11/2003)
4.	Vasavada, Abhay R: 18 articles (09/2014 - 07/2002)
5.	Tham, Clement C Y: 17 articles (08/2015 - 06/2002)
6.	Liu, Yizhi: 14 articles (01/2015 - 05/2002)
7.	Lai, Jimmy S M: 13 articles (01/2015 - 06/2002)
8.	Behndig, Anders: 13 articles (11/2013 - 09/2002)
9.	Hengerer, Fritz H: 12 articles (07/2015 - 12/2011)
10.	Conrad-Hengerer, Ina: 12 articles (07/2015 - 12/2011)

Related Diseases

1.	Cataract (Cataracts) 01/01/2013 - "The results of study confirm an improvement in BCVA after cataract surgery by phacoemulsification in the most of patients. " 05/01/2013 - "Phacoemulsification and intraocular lens implantation is the most effective treatment of cataract.Traditional" 03/01/2012 - "Accordingly, phacoemulsification in posterior polar cataracts, when done carefully, leads to good postoperative results and good visual improvement in most cases." 09/01/2002 - "It is safe and effective for highly myopic patients with cataract to implant a low or negative power Acrysof IOL after phacoemulsification." 01/01/2009 - "Modified NPDS without scleral implant with early Nd:YAG laser goniopuncture and phacoemulsification for treatment of patients with POAG and cataract is a safe and effective procedure with complete success at 6 months."
2.	Glaucoma 04/01/2015 - "iStent implantation resulted in similar IOP reduction to phacoemulsification alone but achieved a significantly greater reduction in glaucoma medications. " 04/01/2005 - "Phacoemulsification in eyes after filtering glaucoma surgery resulted in a stable IOP, a non-significant increase in the number of antiglaucoma medications and a significantly improved BCVA." 06/01/2003 - "Clear corneal or scleral tunnel phacoemulsification in the setting of a preexisting glaucoma filter was associated with improved BCVA, a small but statistically significant increase in IOP, and stability in the number of glaucoma medicines required for IOP control over a minimum follow-up of 1 year." 12/01/1999 - "Combined phacoemulsification and trabeculectomy is an effective and safe approach for obtaining good visual rehabilitation and glaucoma control." 12/01/2014 - "The triple procedure is more effective in lowering intraocular pressure compared to phacoemulsification and trabecular aspiration alone in pseudoexfoliation glaucoma."
3.	Inflammation 03/01/2008 - "Both treatments were equally effective in controlling postoperative inflammation following phacoemulsification. " 05/01/2004 - "With appropriate preoperative and postoperative suppression of inflammation, phacoemulsification and intraocular lens implantation are safe procedures leading to visual improvement in patients with Behçet's disease without preexisting fundus lesions." 06/01/1997 - "Digen seemed to maintain the properties and activities of each individual drug, making it a promising treatment for reducing inflammation after phacoemulsification." 11/01/2013 - "After phacoemulsification there was an improvement in visual acuity, decreasing inflammation, and increased macular thickness and macular volume. " 04/01/1998 - "This study shows that the inflammation in the four groups was very low after phacoemulsification by a corneal incision and attempts to explain the impact of the incision length on the breakdown of blood-aqueous barrier."
4.	Astigmatism 08/01/2011 - "Coaxial microincision phacoemulsification with toric IOL safely and predictably reduced high corneal astigmatism and improved surgical outcomes. " 11/01/2002 - "A combination of intraoperative arcuate keratotomy with steep axis phacoemulsification incision is more effective than steep axis phacoemulsification incision alone in reducing pre-existing astigmatism." 03/01/2005 - "In this study, phacoemulsification combined with pars plana vitrectomy and PC-IOL implantation resulted in greater improvement in vision, less astigmatism change, and fewer postoperative complications." 07/01/2009 - "to evaluate the efficacy of LRI in the management of primary astigmatism when combined with phacoemulsification. " 04/01/2008 - "To compare the efficacy of adding an opposite clear corneal incision (OCCI) on the steep meridian versus performing surgery on the steep meridian alone during phacoemulsification in reducing pre-existing corneal astigmatism. "
5.	Macular Edema 05/01/2007 - "To evaluate the effectiveness of a nonsteroidal antiinflammatory drug (NSAID) on pseudophakic cystoid macular edema (CME) and determine the efficacy when used preoperatively and after uneventful phacoemulsification surgery. " 05/01/2015 - "To study postoperative macular thickness fluctuations measured by spectral-domain optical coherence tomography (SD-OCT) and to investigate a potential correlation among macular edema (ME) incidence, cumulative dissipated energy (CDE) released during phacoemulsification, and vitreoretinal interface status. " 01/01/2010 - "Recent studies do not support the generalized conclusion that phacoemulsification surgery causes progression of retinopathy and macular edema in all diabetic patients. " 06/01/2008 - "The results in this study suggest that AquaLase liquefaction cataract extraction is as safe as standard US phacoemulsification cataract extraction and may carry less risk for the development of postoperative cystoid macular edema. " 11/01/1979 - "An on-going study of results and complications in a series of 1055 cataract extractions, done by Kelman phacoemulsification with up to five and one-half years' follow-up, showed that the incidence of cystoid macular edema (CME) is significantly less when the posterior capsule is left intact. "

Related Drugs and Biologics

1.	Dexamethasone (Maxidex)
2.	Lidocaine (Xylocaine)
3.	Trypan Blue
4.	bevacizumab
5.	Triamcinolone Acetonide (Azmacort)
6.	Ketorolac
7.	Mitomycin (Mitomycin-C)
8.	Diclofenac (SR 38)
9.	Ophthalmic Solutions (Eye Drops)
10.	Ketorolac Tromethamine (Acular)

Related Therapies and Procedures

1.	Intraocular Lens Implantation
2.	Intraocular Lenses (Intraocular Lens)
3.	Vitrectomy
4.	Trabeculectomy (Trabeculoplasty)
5.	Vitreoretinal Surgery