Abstract |
The objective of the study was to determine the prevalence of different forms of dyslipidemia in an urban population of Mexican adolescents. A cross-sectional study was conducted in 1846 students from 8 randomly selected public junior high schools in Mexico City. Anthropometry, blood pressure, and 12-hour fasting lipids and lipoproteins were measured. We studied 770 male and 1076 female adolescents (13.2 +/- 1 years). The most prevalent dyslipidemia was low high-density lipoprotein cholesterol (HDL-C) (<35 mg/dL) either combined with other abnormalities (17.5% for male and 12.9% for female subjects, P < .001) or isolated (13.5% and 9.6% for male and female subjects, respectively, P < .001). Obese subjects showed the highest prevalence of low HDL-C (47.2% for male and 34.4% for female subjects) and of high total cholesterol, low-density lipoprotein cholesterol ( LDL-C), and triglycerides (TG) (19.4%, 27.8%, and 36.1%, respectively, for male subjects; 9.8%, 13.1%, and 24.6%, respectively, for female subjects). Multiple regression analysis showed that waist circumference was negatively associated with HDL-C and positively associated with LDL-C and TG levels, whereas Tanner stages were negatively associated but sex was positively associated with total cholesterol, LDL-C, and TG concentrations. As in Mexican adults, low HDL-C and high TG levels were the most prevalent dyslipidemias. Increased blood lipids over long periods suggest that, as adults, these adolescents will be facing a higher risk for atherosclerosis.
|
Authors | Rosalinda Posadas-Sánchez, Carlos Posadas-Romero, José Zamora-González, Enrique Mendoza-Pérez, Guillermo Cardoso-Saldaña, Liria Yamamoto-Kimura |
Journal | Metabolism: clinical and experimental
(Metabolism)
Vol. 56
Issue 12
Pg. 1666-72
(Dec 2007)
ISSN: 0026-0495 [Print] United States |
PMID | 17998019
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Cholesterol, HDL
- Cholesterol, LDL
- Lipoproteins
- Triglycerides
|
Topics |
- Adolescent
- Alcohol Drinking
(blood, metabolism)
- Blood Pressure
(physiology)
- Body Mass Index
- Child
- Cholesterol, HDL
(blood, metabolism)
- Cholesterol, LDL
(blood, metabolism)
- Cross-Sectional Studies
- Dyslipidemias
(epidemiology, metabolism, physiopathology)
- Female
- Humans
- Lipid Metabolism
- Lipoproteins
(blood, metabolism)
- Male
- Mexico
(epidemiology)
- Prevalence
- Smoking
(blood, metabolism)
- Triglycerides
(blood, metabolism)
- Urban Population
|