[Effectiveness of human leukocytic interferon in children with papillomatosis of the larynx, trachea and bronchi].

Abstract

The results of interferon therapy of 32 children with severe forms of laryngeal, tracheal, and bronchial papillomatosis are very encouraging. Clinical recovery (no relapses during 3 years or longer) was observed in 8 patients, improvement (no relapses during less than 3 years or 2-3-fold prolongation of no-relapse periods) was seen in 12 patients, no changes were recorded in 10 children; data on 2 other patients were too limited or lacking at all. The efficacy of interferon therapy of airways papillomatosis can be further increased, if doses are selected on an individual basis.

• Authors: D G Chireshkin, V P Kuznetsov, E K Onufrieva, A D Pritsker
• Journal: Vestnik otorinolaringologii (Vestn Otorinolaringol) 1991 Sep-Oct Issue 5 Pg. 19-21 ISSN: 0042-4668 [Print] Russia (Federation)
• Vernacular Title: Effektivnost' chelovecheskogo leĭkotsitarnogo interferona pri papillomatoze gortani, trakheĭ i bronkhov u deteĭ.
• PMID: 1755178 (Publication Type: Case Reports, Clinical Trial, English Abstract, Journal Article)

Chemical References

• Interferon-alpha

Topics

• Adolescent
• Bronchial Neoplasms (etiology, secondary, surgery)
• Child
• Child, Preschool
• Female
• Humans
• Interferon-alpha (administration & dosage)
• Laryngeal Neoplasms (pathology, surgery)
• Papilloma (pathology, surgery)
• Postoperative Care
• Preoperative Care
• Tracheal Neoplasms (etiology, secondary, surgery)