[A case of lung adenocarcinoma keeping complete remission by treatment with gefitinib].

Abstract

A 74-year-old smoking man was admitted because of lung cancer with metastatic brain tumor. Examinations for lung cancer and brain tumor showed adenocarcinoma (clinical stage IV). Four courses of chemotherapy were not effective. Administration of gefitinib started from June 2003, but was halted after only two months because of skin rash. Lung tumor disappeared on chest computerized tomography in January 2004 and no recurrence has been detected as of March 2006. This is a rare male super-responder to gefitinib.

• Authors: Koichi Imai, Junichi Ashitani, Shigehisa Yanagi, Tsuyoshi Kodama, Yuka Kyoraku, Arisa Sano, Nobuhiro Matsumoto, Masamitsu Nakazato
• Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Nihon Kokyuki Gakkai Zasshi) Vol. 45 Issue 1 Pg. 71-5 (Jan 2007) ISSN: 1343-3490 [Print] Japan
• PMID: 17313031 (Publication Type: Journal Article)

Chemical References

• Antineoplastic Agents
• Quinazolines
• Gefitinib

Topics

• Adenocarcinoma (drug therapy, secondary)
• Aged
• Antineoplastic Agents (administration & dosage)
• Brain Neoplasms (secondary, surgery)
• Drug Administration Schedule
• Gefitinib
• Humans
• Lung Neoplasms (drug therapy, pathology)
• Male
• Neoplasm Staging
• Quinazolines (administration & dosage)
• Radiosurgery
• Remission Induction
• Smoking