Successful steroid treatment for fibrosing mediastinitis and sclerosing cervicitis.

Abstract

The use of steroids to successfully treat a 75-year-old woman with fibrosing mediastinitis and sclerosing cervicitis causing a stricture of the left common carotid artery is reported. Biopsy specimens showed collagenous fibers and fibroblasts with moderate infiltration of lymphocytes. The mediastinal and neck lesions were significantly reduced, with almost complete resolution of arterial stricture, 3 months after initiating administration of prednisolone at 20 mg/d.

• Authors: Koei Ikeda, Hiroaki Nomori, Takeshi Mori, Hironori Kobayashi, Kazunori Iwatani, Kentaro Yoshimoto, Masakazu Yoshioka
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 83 Issue 3 Pg. 1199-201 (Mar 2007) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 17307498 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Prednisolone

Topics

• Aged
• Carotid Artery Diseases (etiology)
• Carotid Artery, Common
• Constriction, Pathologic
• Female
• Fibrosis
• Glucocorticoids (therapeutic use)
• Humans
• Mediastinitis (complications, diagnosis, drug therapy, pathology)
• Positron-Emission Tomography
• Prednisolone (therapeutic use)
• Radiography, Thoracic
• Sclerosis
• Treatment Outcome
• Uterine Cervicitis (complications, diagnosis, drug therapy, pathology)