Abstract | OBJECTIVE: To estimate prospectively the effect of first delivery on subjective bladder function and to assess the influence of subsequent deliveries and obstetric events METHODS: We performed a prospective, observational cohort study. During a 10-week period in 1995, 304 of 309 eligible primiparous women (98%) entered the study at the postpartum maternity ward and completed a bladder function questionnaire. The 10-year observational period was completed by 246 of 304 subjects (81%). RESULTS: Prevalence of moderate-severe stress urinary incontinence increased from 5 of 304 subjects (2%) at baseline to 27 of 229 (12%) at 10 years follow-up (P < .001). Prevalence of moderate-severe urinary urgency increased from 0 subjects (0%) at baseline to 31 of 229 (13%) at the 10-year follow-up (P < .001). The relative risk (RR) (adjusted for maternal age and parity) of moderate to severe urinary incontinence increased significantly 10 years after first delivery (RR 5.8, 95% confidence interval [CI] 1.2-33.7). At multivariable analysis adjusted for age and parity, stress urinary incontinence symptoms at 9 months and 5 years follow-up were independently associated with the presence of symptoms at 10 years after index delivery (RR 13.3, 95% CI 3.9-33.1 and RR 14.1, 95% CI 2.5-18.8, respectively). Number of vaginal deliveries or other obstetric covariates did not affect the risk of stress urinary incontinence or urinary urgency. CONCLUSION: Vaginal delivery is independently associated with a significant long-term increase in stress urinary incontinence symptoms, as well as urinary urgency, regardless of maternal age or number of deliveries. LEVEL OF EVIDENCE: II-2.
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Authors | Daniel Altman, Asa Ekström, Catharina Gustafsson, Annika López, Christian Falconer, Jan Zetterström |
Journal | Obstetrics and gynecology
(Obstet Gynecol)
Vol. 108
Issue 4
Pg. 873-8
(Oct 2006)
ISSN: 0029-7844 [Print] United States |
PMID | 17012448
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Cohort Studies
- Delivery, Obstetric
(adverse effects)
- Female
- Humans
- Multivariate Analysis
- Parity
- Pregnancy
- Regression Analysis
- Risk Factors
- Urinary Bladder
(injuries)
- Urinary Incontinence, Stress
(epidemiology, etiology)
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