Abstract | BACKGROUND AND AIM: MATERIAL AND METHOD: A prospective study during 14 months has been designed with the cooperation of dermatologic, internal medicine and cardiology departments of the Aristide Le Dantec hospital of Dakar. Platelets count (Beckmann Coulter analyzer), activated partial thromboplastin time (Diagnostiga stago analyzer) and antiphospholipids antibodies (Elisa) were determined. RESULTS: 37 patients affected by lupus were included in this study with a net feminine prevalence (89%); 8 (14.6%) had APL's significant results and 20 presented an echographic heart abnormality. The analysis of our data did not reveal an increased risk of cardiac diseases among APL positive lupic patients as compared to the negative group (p = 1). CONCLUSION: The presence of APL in patients with systemic lupus does not so seem to be an independant risk factor of heart diseases.
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Authors | A O Touré, D Doupa, S Diop, A Kane, A Kane, M M Ka, T Dieye, D Thiam, L Diakhaté |
Journal | Annales de biologie clinique
(Ann Biol Clin (Paris))
2006 May-Jun
Vol. 64
Issue 3
Pg. 231-5
ISSN: 0003-3898 [Print] France |
Vernacular Title | Relation lupus-anticorps antiphospholipides et cardiopathie lupique. |
PMID | 16698558
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antibodies, Antiphospholipid
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Topics |
- Adolescent
- Adult
- Aged
- Antibodies, Antiphospholipid
(blood)
- Cross-Sectional Studies
- Female
- Heart Diseases
(blood, complications)
- Humans
- Lupus Erythematosus, Systemic
(complications, immunology)
- Male
- Middle Aged
- Prospective Studies
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