[Plasmapheresis and amino acid mixtures of "Aminosteril-Hepa" type preparations in treating hepatic encephalopathy].

Abstract

An effect of Aminosteril-Hepa intravenous infusions or plasmapheresis on selected amino acids, ammonia, alpha-aminonitrogen serum levels and serum GGTP activity was analysed in 28 patients with liver cirrhosis with and without hepatic encephalopathy. The patients were given protein controlled dietary treatment. It was found, that plasmapheresis exerted more potent effect on previously elevated ammonia and serum alpha-aminonitrogen levels as well as serum GGTP activity than intravenous infusions of Aminosteril-Hepa. It was clearly seen in patients with liver cirrhosis without hepatic encephalopathy. Aminosteril-Hepa intravenous infusions decreased serum glutamine levels to higher degree than plasmapheresis. Both types of therapy have had no significant effect on serum phenylalanine, tyrosine, and tryptophan levels in all patients.

• Authors: P Boroń, R Flisiak, E Bobrowska, W Hilgier, T Szpakowicz, B Pytel
• Journal: Polski tygodnik lekarski (Warsaw, Poland : 1960) (Pol Tyg Lek) 1991 Dec 26-30 Vol. 46 Issue 50-52 Pg. 984-6 ISSN: 0032-3756 [Print] Poland
• Vernacular Title: Plazmafereza i mieszanki aminokwasów typu preparatu "Aminosteril-Hepa" w leczeniu encefalopatii watrobowej.
• PMID: 1669187 (Publication Type: English Abstract, Journal Article)

Chemical References

• Amino Acids
• Amino Acids, Branched-Chain
• aminosteril-hepa
• Glutamine

Topics

• Amino Acids (therapeutic use)
• Amino Acids, Branched-Chain (therapeutic use)
• Glutamine (blood)
• Hepatic Encephalopathy (blood, etiology, therapy)
• Humans
• Liver Cirrhosis (blood, complications, therapy)
• Plasmapheresis