Round window membrane and labyrinthine pathological changes: an overview.

Abstract

The round window membrane is considered the most likely pathway from the middle to the inner ear. Various substances placed in the middle ear have been seen to pass through the round window membrane. Once toxic substances or inflammatory mediators such as cytokines and nitric oxide enter the inner ear, various inner ear sequelae such as labyrinthitis, endolymphatic hydrops, sensorineural hearing loss or more insidious diseases can occur.

• Authors: Sebahattin Cureoglu, Patricia A Schachern, Alessandra Rinaldo, Vladimir Tsuprun, Alfio Ferlito, Michael M Paparella
• Journal: Acta oto-laryngologica (Acta Otolaryngol) Vol. 125 Issue 1 Pg. 9-15 (Jan 2005) ISSN: 0001-6489 [Print] England
• PMID: 15799567 (Publication Type: Journal Article, Review)

Chemical References

• Cytokines
• Nitric Oxide

Topics

• Bacterial Infections (complications)
• Basilar Membrane (metabolism, pathology)
• Cell Membrane Permeability
• Cytokines (metabolism)
• Humans
• Labyrinthitis (metabolism, microbiology, pathology)
• Nitric Oxide (metabolism)
• Otitis Media (metabolism, pathology)
• Round Window, Ear (metabolism, pathology)