Reductive effect of body weight in C57BL/6J mice fed a high-fat diet by Saesaengmyung Diet.

Abstract

The Saesaengmyung Diet (SD) is a newly developed dietary product to help control weight. The aim of this study was to evaluate whether SD combined with a high-fat (HF) diet could influence body weight, fat accumulation, and glucose levels in blood. C57BL/6J mice were fed for 8 weeks with a standard diet, an HF diet, and an HF + 10% or HF + 20% SD diet. Body weight was recorded weekly, and plasma levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and glucose were analyzed at the end of the study. Weight increases in the 10% or 20% SD group were significantly less than in the HF diet group (p < 0.05). Plasma total cholesterol level significantly decreased by 33.5% in the 10% SD group and 38.8% in the 20% SD group, but the LDL cholesterol, HDL cholesterol, and glucose levels in the SD groups were not significantly changed. Our findings indicate that SD may be beneficial to overweight individuals in the reduction of weight gain induced by an HF diet.

• Authors: Hyo-Jin An, Na-Hyung Kim, Yun-Kyung Kim, Yeoung-Su Lyu, Taekyun Shin, Seung-Heon Hong, Hyung-Min Kim
• Journal: Canadian journal of physiology and pharmacology (Can J Physiol Pharmacol) Vol. 83 Issue 2 Pg. 161-5 (Feb 2005) ISSN: 0008-4212 [Print] Canada
• PMID: 15791289 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Blood Glucose
• Dietary Fats
• Plant Preparations
• Cholesterol
• Aspartate Aminotransferases
• Alanine Transaminase

Topics

• Alanine Transaminase (blood)
• Animals
• Aspartate Aminotransferases (blood)
• Blood Glucose (analysis)
• Cholesterol (blood)
• Diet
• Dietary Fats (administration & dosage)
• Male
• Mice
• Mice, Inbred C57BL
• Plant Preparations (pharmacology)
• Weight Loss