Abstract | OBJECTIVE: STUDY DESIGN: We pooled information on the self-reported history of endometriosis from 4 population-based case-controlled studies of incident epithelial ovarian cancer, comprising 2098 cases and 2953 control subjects. We obtained data on oral contraceptive use, childbearing, breastfeeding, gynecologic surgical procedures, and other reproductive factors on each woman. Multivariable unconditional logistic regression was used to calculate odds ratios and 95% CI for ovarian cancer among women with endometriosis compared with women without endometriosis. Similar methods were used to assess the frequencies of risk factors among women with and without endometriosis. Adjustments were made for age, parity, oral contraceptive use, tubal ligation, family history of ovarian cancer, and study site. RESULTS: CONCLUSION:
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Authors | Francesmary Modugno, Roberta B Ness, Glenn O Allen, Joellen M Schildkraut, Faith G Davis, Marc T Goodman |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 191
Issue 3
Pg. 733-40
(Sep 2004)
ISSN: 0002-9378 [Print] United States |
PMID | 15467532
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Adult
- Aged
- Case-Control Studies
- Contraceptives, Oral
(administration & dosage)
- Endometriosis
(complications)
- Female
- Humans
- Hysterectomy
- Logistic Models
- Middle Aged
- Odds Ratio
- Ovarian Neoplasms
(epidemiology)
- Pregnancy
- Reproduction
- Risk Factors
- Sterilization, Tubal
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