Cerebral atypical teratoid/rhabdoid tumor of infancy: long-term survival after multimodal treatment, also including triple intrathecal chemotherapy and gamma knife radiosurgery--case report.

Abstract

Cerebral atypical teratoid/rhabdoid tumors (AT/RT) of infancy are highly malignant and have a poor prognosis. The authors report on one case with long-term survival. The patient was a 1 year-old boy presenting with a large AT/RT in the right temporal lobe. He was treated with complete surgery, followed by multiagent chemotherapy. Later he had a second resection and intrathecal chemotherapy and Gamma knife radiosurgery was added to the treatment. Except for a well-controlled temporal epilepsy, the boy is doing well after 6 years follow-up. AT/RT should be treated in a multimodal way. Intrathecal chemotherapy and Gamma knife radiosurgery of single recurrent or residual tumors might increase survival.

• Authors: Asle Hirth, Paal-Henning Pedersen, Knut Wester, Sverre Mörk, Jon Helgestad
• Journal: Pediatric hematology and oncology (Pediatr Hematol Oncol) Vol. 20 Issue 4 Pg. 327-32 (Jun 2003) ISSN: 0888-0018 [Print] England
• PMID: 12746165 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Antineoplastic Agents (therapeutic use)
• Brain Neoplasms (mortality, pathology, therapy)
• Combined Modality Therapy
• Humans
• Infant
• Injections, Spinal
• Magnetic Resonance Imaging
• Male
• Neoplasm Recurrence, Local
• Radiosurgery
• Rhabdoid Tumor (mortality, pathology, therapy)
• Survivors
• Teratoma (mortality, pathology, therapy)
• Tomography, X-Ray Computed