[Mucinous adenocarcinoma of the urachus].

Abstract

OBJECTIVE:

The Adenocarcinoma of the Urachus is very rare tumor, with an incidence of 1/5,000,000 inhabitants, represents less than 0.001 of all types of bladder cancer.

CASE REPORT:

A 51 year old man with a chronic history of suprapubic pain and hematuria. Physical examination and excretory urography were normal. The cystoscopy demonstrated a oedematosa area in cupola of bladder wall. The transuretral biopsy was moderately differentiated adenocarcinoma, with positive antibody to CK7 and CK20, the carcinoembryonic antigen was 6.6 ng/ml. Extended partial cystectomy was done, followed for chemotherapy and radiotherapy.

CONCLUSIONS:

The treatment of adenocarcinoma of the urachus with a combination of extended partial cystectomy, chemotherapy and radiation, is a effective treatment.

• Authors: A Ojea Calvo, A Núñez López, F Domínguez Freire, A Alonso Rodrigo, B Rodríguez Iglesias, J Benavente Delgado, J M Barros Rodríguez, A González Piñeiro, M Otero García, D López Bellido
• Journal: Actas urologicas espanolas (Actas Urol Esp) Vol. 27 Issue 2 Pg. 142-6 (Feb 2003) ISSN: 0210-4806 [Print] Spain
• Vernacular Title: Adenocarcinoma mucinoso de uraco.
• PMID: 12731329 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Biomarkers, Tumor
• Carcinoembryonic Antigen
• Intermediate Filament Proteins
• KRT20 protein, human
• KRT7 protein, human
• Keratin-20
• Keratin-7
• Neoplasm Proteins
• Deoxycytidine
• Keratins
• Cisplatin
• Gemcitabine

Topics

• Adenocarcinoma, Mucinous (chemistry, pathology, therapy)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Biomarkers, Tumor (analysis)
• Carcinoembryonic Antigen (analysis)
• Chemotherapy, Adjuvant
• Cisplatin (administration & dosage)
• Combined Modality Therapy
• Cystectomy
• Deoxycytidine (administration & dosage, analogs & derivatives)
• Humans
• Intermediate Filament Proteins (analysis)
• Keratin-20
• Keratin-7
• Keratins (analysis)
• Male
• Middle Aged
• Neoplasm Proteins (analysis)
• Radiotherapy, Adjuvant
• Urachus (pathology)
• Urinary Bladder Neoplasms (chemistry, pathology, therapy)
• Gemcitabine