Abstract | INTRODUCTION: MATERIAL AND METHODS: A total of 119 patients were evaluated. Nobody dropped out. In all patients the following parameters were assessed; age, sex, treatment with anti-retroviral drugs, performed an anthropometric evaluation (weight, tricipital skinfold, midarm circumference, and body mass index (BMI)) and a biochemical evaluation ( glucose, albumin, prealbumin, transferrin, total proteins, limphocytes and count of CD4). All patients received instruction in 24-hour written food record keeping. RESULTS: Patients had an average age 37.9 +/- 9.9 years, weight 64.5 +/- 13.2 kg and body mass index 22.5 +/- 3.5. Levels of total proteins, albumin, prealbumin y transferrin were normal. Percentile distribution of anthropometric parameters showed a deep depletion in muscular protein compartiment, 53.1% of patients had tricipital skinfold under P 50, 91.8% had midarm muscle circumference under P 50. The correlation analysis among dietary intake and immune status, showed a positive association among vitamin A intake and vitamin D with CD4+ (r = 0.35; p < 0.01) and (r = 0.51; p < 0.001), respectively. In the multivariant analysis with dependent variable (CD4 count), only vitamin D remained in the model (F = 16.99; p < 0.001), with an increase of 34 (CI 95%: 5.81-167.3) CD4+ (count/uL) with each microgram of vitamin D intake, adjusted by age, sex, energy and protein intake, and anti-retroviral drugs. CONCLUSION:
Vitamin A, and D intakes were correlated with CD4 count, only vitamin D remained as a independent predictor parameter in a in multivariant model.
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Authors | D A de Luis, P Bachiller, R Aller, J de Luis, O Izaola, M C Terroba, L Cuellar, M González Sagrado |
Journal | Nutricion hospitalaria
(Nutr Hosp)
2002 Nov-Dec
Vol. 17
Issue 6
Pg. 285-9
ISSN: 0212-1611 [Print] Spain |
Vernacular Title | Relación entre la ingesta de micronutrientes y el recuento de CD4 en una población de pacientes con infección por VIH. |
PMID | 12514921
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Micronutrients
- Trace Elements
- Vitamin A
- Vitamin D
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Topics |
- Adult
- Anthropometry
- CD4 Lymphocyte Count
- CD4-Positive T-Lymphocytes
(immunology)
- Energy Intake
- Female
- HIV Infections
(immunology)
- HIV-1
(physiology)
- Humans
- Male
- Micronutrients
(administration & dosage)
- Nutritional Status
- Trace Elements
(blood)
- Vitamin A
(administration & dosage)
- Vitamin D
(administration & dosage)
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