Papillon-Lefévre syndrome: the response to acitretin.

Abstract

Papillon-Lefévre syndrome is a rare autosomal recessive disease comprising palmoplantar keratoderma and periodontitis. Palmoplantar keratoderma can be severe, necessitating systemic treatment. Different systemic retinoids were found to be highly efficacious. We describe the successful use of acitretin in one patient who had severe palmoplantar keratoderma, with maintenance of the improvement using topical treatment.

• Authors: Sultan Al-Khenaizan
• Journal: International journal of dermatology (Int J Dermatol) Vol. 41 Issue 12 Pg. 938-41 (Dec 2002) ISSN: 0011-9059 [Print] England
• PMID: 12492996 (Publication Type: Case Reports, Journal Article)

Chemical References

• Keratolytic Agents
• Acitretin

Topics

• Acitretin (therapeutic use)
• Child, Preschool
• Female
• Humans
• Keratolytic Agents (therapeutic use)
• Papillon-Lefevre Disease (drug therapy, pathology)