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A case of refractory hypothyroidism requiring daily intravenous thyroxine.

Abstract
Most patients with hypothyroidism respond to administration of oral thyroxine at a maintenance dose of 50-175 micrograms/day. This is the first documented patient with post-operative hypothyroidism who required about 10 times the standard dose of thyroxine, and whose symptoms only resolved when intravenous thyroxine was administered daily. Our findings support the benefits of daily intravenous therapy with thyroxine in this case.
AuthorsT Nagaoka, H Miyakoshi, T Takamura, Y Nagai, S Matsushita, S Kaneko, K Kobayashi
JournalThe Journal of international medical research (J Int Med Res) 2002 Jul-Aug Vol. 30 Issue 4 Pg. 463-5 ISSN: 0300-0605 [Print] England
PMID12235934 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Triiodothyronine
  • Thyrotropin
  • Thyroxine
Topics
  • Adult
  • Female
  • Humans
  • Hypothyroidism (drug therapy)
  • Injections, Intravenous
  • Thyrotropin (blood)
  • Thyroxine (administration & dosage, blood, therapeutic use)
  • Triiodothyronine (blood)

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