Abstract | OBJECTIVE: METHODS: RESULTS: All BCC, including 11 cases of superficial lesions and 29 solid lesions, achieved complete reaction (CR) by 1-4 times of the ALA- PDT. Except one patient with adenoid SCC (grade III), all SCC (grade I and grade II) patients achieved complete remission by 3-6 times of ALA- PDT. All Bowen diseases achieved complete reaction by 1-4 times. Although for Paget diseases it could not cure the disease simply by ALA- PDT, it could control the symptoms. The recurrence rates were 11% (4/34) for BCC, and 22% (7/32) for SCC by following up 1-3 years after the therapy. The continuous therapy is still effective. CONCLUSIONS: ALA- PDT is an effective, non-traumatic treatment for patients with BCC, SCC, Bowen and Paget diseases. It is especially suitable for older and weaker patients or those who are not tolerable to other therapies. It also has a unique advantage for tumors in specific anatomical areas. It is a new alternative modality for skin cancer therapies.
|
Authors | Shizheng Xu, Xiuli Wang, Wei Xu, Yumin Xia, Chunrong Zhang |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 115
Issue 8
Pg. 1141-5
(Aug 2002)
ISSN: 0366-6999 [Print] China |
PMID | 12215278
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Aminolevulinic Acid
(therapeutic use)
- Carcinoma, Basal Cell
(drug therapy)
- Carcinoma, Squamous Cell
(drug therapy)
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Photochemotherapy
(adverse effects)
- Skin Neoplasms
(drug therapy)
|