Solitary fibrous tumor in the mental region.

Abstract

Solitary fibrous tumor (SFT) is a rare, benign, soft tissue tumor that most commonly occurs in the pleura; however, it has recently been described in other sites of the body. To date, eight examples of oral SFT have been reported. This paper is a description of the first case of an SFT occurring as a soft tissue tumor in the mental region. Histologically, the tumor was composed predominantly of rather uniform spindle-shaped fibroblastic cells arranged in vague fascicles or in a haphazard fashion, intermingled with abundant collagen fibers. Immunohistochemically, the tumor cells were positive for CD34 and vimentin, and weakly positive for muscle actin and alpha-smooth muscle actin. The diagnosis of SFT may be difficult as this tumor shares a number of histological features with other soft tissue tumors. Awareness of its occurrence in the oral cavity is important so that confusion with other spindle cell neoplasms can be avoided.

• Authors: M Hirano, J Tanuma, T Shimoda, K Sugihara, M Tsuneyoshi, M Kitano
• Journal: Pathology international (Pathol Int) Vol. 51 Issue 11 Pg. 905-8 (Nov 2001) ISSN: 1320-5463 [Print] Australia
• PMID: 11844061 (Publication Type: Case Reports, Journal Article)

Chemical References

• Actins
• Antigens, CD34
• Biomarkers, Tumor
• Vimentin

Topics

• Actins (analysis)
• Antigens, CD34 (analysis)
• Biomarkers, Tumor
• Chin (pathology)
• Facial Neoplasms (chemistry, pathology, surgery)
• Female
• Humans
• Immunoenzyme Techniques
• Middle Aged
• Neoplasms, Fibrous Tissue (chemistry, pathology, surgery)
• Soft Tissue Neoplasms (chemistry, pathology, surgery)
• Treatment Outcome
• Vimentin (analysis)