[Neostigmine treatment of acute pseudo-obstruction of colon (Ogilvie syndrome)].

Abstract

In a 77-year-old male patient with Parkinson's disease and with acute pseudo-obstruction of the colon (Ogilvie's syndrome) conservative therapy was ineffective. Neostigmine was recently shown to be effective and safe for the treatment of Ogilvie's syndrome. Intravenous neostigmine treatment caused a prompt clinical and radiological response in the patient. Early recognition of the condition and prompt neostigmine treatment if conservative measures fail is important to reduce the risk of bowel perforation.

• Authors: J J Koornstra, N S Klaver, J C ter Maaten, A J Limburg, E J van der Jagt, T S van der Werf
• Journal: Nederlands tijdschrift voor geneeskunde (Ned Tijdschr Geneeskd) Vol. 145 Issue 12 Pg. 586-9 (Mar 24 2001) ISSN: 0028-2162 [Print] Netherlands
• Vernacular Title: Neostigmine voor de behandeling van acute pseudo-obstructie van het colon (Ogilvie-syndroom).
• PMID: 11294000 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Parasympathomimetics
• Neostigmine

Topics

• Aged
• Colonic Pseudo-Obstruction (complications, drug therapy)
• Humans
• Infusions, Intravenous
• Intestinal Perforation (prevention & control)
• Male
• Neostigmine (administration & dosage, therapeutic use)
• Parasympathomimetics (administration & dosage, therapeutic use)
• Parkinson Disease (complications)
• Treatment Outcome