Abstract | BACKGROUND/AIMS: METHODOLOGY: Between 1975 and 1997, nineteen of 688 patients (2.8%) treated for bleeding esophageal varices had cirrhosis and irresectable hepatocellular carcinoma. There were 13 men and 6 women; median age, 42 years (range: 20-81). Eight patients were Child's-Pugh grade B and 11 grade C; 11 patients were Okuda stage II and 8 stage III. RESULTS: In 13 patients (68.4%) bleeding was controlled by injection sclerotherapy after a mean of 3 injections (range: 1-5), and of these esophageal varices were completely eradicated in 7 patients (53.9%), none of whom rebled. Twelve patients (63%) were discharged from hospital and had a mean survival of 100 days. Seven patients died in hospital, 5 of liver failure precipated by recurrent bleeding and 2 of hepatocellular carcinoma. Median survival for Child's-Pugh grade B patients was 80 days (range: 9-405) compared to 28 days (range: 8-117) for the grade C (P = 0.25). CONCLUSIONS:
|
Authors | M H Letier, J E Krige, E R Lemmer, J Terblanche |
Journal | Hepato-gastroenterology
(Hepatogastroenterology)
2000 Nov-Dec
Vol. 47
Issue 36
Pg. 1680-4
ISSN: 0172-6390 [Print] Greece |
PMID | 11149031
(Publication Type: Journal Article)
|
Topics |
- Adult
- Aged
- Carcinoma, Hepatocellular
(complications, therapy)
- Esophageal and Gastric Varices
(etiology, therapy)
- Female
- Gastrointestinal Hemorrhage
(etiology, therapy)
- Humans
- Liver Cirrhosis
(complications)
- Liver Neoplasms
(complications, therapy)
- Male
- Middle Aged
- Palliative Care
- Retrospective Studies
- Sclerotherapy
(methods)
|