Value of prednisone in combination chemotherapy of stage IV Hodgkin's disease. Report from the British National Lymphoma Investigation.

Abstract	A combination of mustine, vincristine (Oncovin), procarbazine, and prednisione (MOPP) and the same combination without prednisone (MOP) were compared in the treatment of stage IV Hodgkin's disease in a prospective randomized trial. The complete remission rates were 80% with MOPP and 44% with MOP; the difference was highly significant. Prednisone seems to be an important component of the MOPP combination in the management of stage IV Hodgkin's disease.
Authors
Journal	British medical journal (Br Med J) Vol. 3 Issue 5980 Pg. 413-4 (Aug 16 1975) ISSN: 0007-1447 [Print] England
PMID	1098721 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References	Procarbazine Mechlorethamine Vincristine Prednisone
Topics	Clinical Trials as Topic Drug Evaluation Drug Therapy, Combination Hodgkin Disease (drug therapy) Humans Mechlorethamine (therapeutic use) Prednisone (therapeutic use) Procarbazine (therapeutic use) Prospective Studies Remission, Spontaneous Vincristine (therapeutic use)

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