Uterine Duplication Anomalies

A group of anomalies in which the UTERUS is duplicated due to abnormal fusion of the MULLERIAN DUCT during embryonic development.

Also Known As:

Anomaly, Uterine Duplication; Double Wombs; Duplication Anomaly, Uterine; Uterine Duplication Anomaly; Uterus, Double; Womb, Double; Double Uterus; Double Womb

Networked: 21 relevant articles (0 outcomes, 4 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Hematocolpos
2.	Myoma
3.	Pelvic Pain
4.	Suppuration
5.	Rupture

Experts

1.	Bonan, Paulo Rogério Ferreti: 1 article (05/2015)
2.	Coletta, Ricardo Della: 1 article (05/2015)
3.	Ferreira, Victor Yuri Nicolau: 1 article (05/2015)
4.	Leon, Jorge Esquiche: 1 article (05/2015)
5.	Monteiro, Larissa Cavalcanti: 1 article (05/2015)
6.	Pereira, Laudenice Lucena: 1 article (05/2015)
7.	Check, J H: 1 article (01/2014)
8.	Choe, J K: 1 article (01/2014)
9.	Cohen, R: 1 article (01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Uterine Duplication Anomalies:

1.	PlasticsIBA 07/01/1952 - "Plastic unification of double uterus; a study of 123 collected and five personal cases." 08/01/1985 - "Plastic unification of a double uterus and the outcome of pregnancy." 07/01/1959 - "Plastic repair of double uterus." 10/01/1956 - "Reproductive difficulties in double uterus; the place of plastic reconstruction." 07/01/1987 - " Surgical removal of uterine myoma, plastic unification of double uterus, and immunological therapy were among the methods used for treating infertility. "
2.	Estrogens (Estrogen)FDA Link 02/01/1976 - "Two non-estrogen-related cases had coexisting congenital malformations with double uterus and vagina and unilateral renal agenesis. " 03/01/1971 - "[Estrogen and androgen induction of biosynthesis of nuclear and cytoplasmic RNA by the rat uterus: double-label studies]." 01/01/2014 - "To determine if the treatment with uterine infusion of granulocyte colony-stimulating factor (G-CSF) can improve endometrial thickness in an infertile woman with a double uterus, who consistently showed a thin endometrium in the late proliferative phase either in controlled ovarian hyperstimulation (COH) IVF-ET cycles or with graduated estrogen/sildenafil protocols for frozen embryo transfer (ET). "
3.	AndrogensIBA 01/01/1987 - "A case is reported of bilateral dermoid cysts in a 21-year-old woman with a double uterus, hirsutism, oligomenorrhea and markedly elevated serum-androgens. " 03/01/1971 - "[Estrogen and androgen induction of biosynthesis of nuclear and cytoplasmic RNA by the rat uterus: double-label studies]."
4.	RNA (Ribonucleic Acid)IBA 03/01/1971 - "[Estrogen and androgen induction of biosynthesis of nuclear and cytoplasmic RNA by the rat uterus: double-label studies]."
5.	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/01/2014 - "To determine if the treatment with uterine infusion of granulocyte colony-stimulating factor (G-CSF) can improve endometrial thickness in an infertile woman with a double uterus, who consistently showed a thin endometrium in the late proliferative phase either in controlled ovarian hyperstimulation (COH) IVF-ET cycles or with graduated estrogen/sildenafil protocols for frozen embryo transfer (ET). "
6.	Oxytocin (Pitocin)FDA LinkGeneric 01/01/1981 - "Oxytocin-induced rupture of a double uterus in a primigravida."
7.	Diethylstilbestrol (Stilbestrol)FDA Link 03/01/1993 - "Fifteen patients with double uterus (13 septate and two bicornuate) and three with T-shaped uterine cavities after diethylstilbestrol exposure underwent abdominal metroplasty (Jones or Strassman techniques) for the repair of the uterus during the period August 1983 through August 1991. "
8.	Capsules (Microcapsules)IBA 05/01/2015 - "A histopathological examination revealed a dense fibrous capsule and a single female filarial worm showing double uterus appearance, neural plaque, well-developed musculature and intestinal apparatus. "
9.	Sildenafil Citrate (Viagra)FDA Link 01/01/2014 - "To determine if the treatment with uterine infusion of granulocyte colony-stimulating factor (G-CSF) can improve endometrial thickness in an infertile woman with a double uterus, who consistently showed a thin endometrium in the late proliferative phase either in controlled ovarian hyperstimulation (COH) IVF-ET cycles or with graduated estrogen/sildenafil protocols for frozen embryo transfer (ET). "
10.	A 17 (A-17)IBA 07/01/1999 - "A 17 year old patient who had complained of vaginal pus-like discharge on and off for 1 year was diagnosed by MRI to have a double uterus with obstructed right hemivagina and ipsilateral renal agenesis. "

Therapies and Procedures

1.	Therapeutics 08/31/1966 - "[Further contribution to the study and therapy of double uterus bicornis (pseudodidelphia) with partially imperforate vagina, site of hematocolpos]." 07/01/1987 - " Surgical removal of uterine myoma, plastic unification of double uterus, and immunological therapy were among the methods used for treating infertility. "
2.	Nursing Care 06/24/1976 - "Nursing care study: double uterus."
3.	Laparotomy 12/01/1994 - "Peritoneal-fluid samples were collected during laparoscopy or laparotomy from 14 patients with endometriosis and from 11 patients with other diseases (5 with myoma uteri, 5 with benign ovarian cysts and 1 with a double uterus) as controls. "
4.	Intrauterine Devices (Intrauterine Device) 11/17/1986 - "The double uterus should always be considered in cases of severe dysmenorrhoea and chronic pelvic pain; in cases of the failure of intrauterine contraceptive devices; in cases of a symptomatic or asymptomatic pelvic mass that is inseparable from the uterus; in cases where termination of pregnancy has been unsuccessful; and in cases of cervical incompetence. "
5.	Hysterectomy 07/01/1947 - "Full-term labor after a subtotal hysterectomy in a double uterus."