meayamycin B

structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/20/2014 - "This action was previously associated with the cytotoxicity of meayamycin B in non-small cell lung carcinoma cell lines. " 05/17/2013 - "The resulting proapoptotic cellular environment was further exploited; when meayamycin B was combined with Bcl-x(L) inhibitor ABT-737, the combination treatment triggered apoptosis in nonsmall cell lung cancer A549 and H1299 cells that were otherwise resistant to ABT-737. "
2.	Leukemia 08/20/2014 - "Meayamycin B switches the splicing pattern of myeloid cell leukemia factor 1 (MCL1) pre-mRNA. "
3.	Squamous Cell Carcinoma of Head and Neck 08/20/2014 - "In a panel of seven HNSCC cell lines, the combination of meayamycin B and ABT-737 rapidly triggered a Bax/Bak-mediated apoptosis that overcame the resistance from HPV16-positive HNSCC against each agent alone. "

1.	ABT-737
2.	RNA Precursors (Precursor, mRNA)