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Morpholines

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Also Known As:

Tetrahydro 1,4 Oxazines; Tetrahydro-1,4-Oxazines

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Oxazines: 2
    - Morpholines: 4

Experts

1.	Zhang, Lili: 1 article (11/2010)
2.	Li, Hongmei: 1 article (11/2010)
3.	Cole, David: 1 article (11/2010)
4.	Nomeir, Amin A: 1 article (11/2010)
5.	Song, Lixin: 1 article (11/2010)
6.	Xu, Ruo: 1 article (11/2010)
7.	Clader, John W: 1 article (11/2010)
8.	Greenlee, William J: 1 article (11/2010)
9.	Schell, Wiley A: 1 article (01/2010)
10.	Collins, Cathy: 1 article (01/2010)

Related Diseases

1.	Inflammation 10/01/2005 - "Effect of some biologically interesting substituted tetrahydro-1,4-oxazines on drug metabolising enzymes and on inflammation."
2.	Hypersensitivity (Allergy) 01/01/2010 - "Pharmacological or genetic impairment of Pkc1 conferred hypersensitivity to multiple drugs that target synthesis of the key cell membrane sterol ergosterol, including azoles, allylamines, and morpholines. "
3.	Ataxia (Dyssynergia) 07/01/1984 - "Ataxia potencies of all PCP-related compounds ranged from 0.05 to 2.15 X PCP and durations of action ranged from 18 to 65 min. N-ethyl-1-phenylcyclohexylamine, 1-[1-(2-thienyl)-cyclohexyl]-piperidine and 1-[1-(2-thienyl)-cyclohexyl]-pyrrolidine were most potent and least potent were 1-(1-phenyl-cyclohexyl)-4-methylpiperidine, the phenyl and thienyl morpholines and 4-phenyl-4-piperidinocyclohexanol. "
4.	Alzheimer Disease (Alzheimer's Disease) 11/15/2010 - "Design and synthesis of cis-2,6-disubstituted N-arylsulfonyl morpholines as novel γ-secretase inhibitors for the potential treatment of Alzheimer's disease (AD) is reported. "

Related Drugs and Biologics

1.	Amyloid Precursor Protein Secretases (beta-Secretase)
2.	Ergosterol (Lumisterol)
3.	Enzymes
4.	Azoles
5.	piperidine
6.	pyrrolidine
7.	4-phenyl-4-piperidinocyclohexanol
8.	N-ethyl-1-phenylcyclohexylamine